Blar i forfatter "Johnsen, Håkon Sandbukt"

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    • Biomarkers of major bleeding after incident venous thromboembolism 

      Johnsen, Håkon Sandbukt (Doctoral thesis; Doktorgradsavhandling, 2021-03-23)
      Major bleeding (MB) events are feared and potentially fatal complications of anticoagulant treatment in patients with venous thromboembolism (VTE). Even though several clinical risk factors are associated with MB risk, the predictive power of currently available risk assessment models remain limited for VTE. The aim of this thesis was to identify biomarkers of MB risk during the first year after an ...

    • D-Dimer Measured at Diagnosis of Venous Thromboembolism is Associated with Risk of Major Bleeding 

      Johnsen, Håkon Sandbukt; Hindberg, Kristian; Bjøri, Esben; Brodin, Ellen Elisabeth; Brækkan, Sigrid Kufaas; Morelli, Vania Maris; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-25)
      Identification of patients at risk of major bleeding is pivotal for optimal management of anticoagulant therapy in venous thromboembolism (VTE). Studies have suggested that D-dimer may predict major bleeding during anticoagulation; however, this is scarcely investigated in VTE patients. We aimed to investigate the role of D-dimer, measured at VTE diagnosis, as a predictive biomarker of major bleeding. ...

    • Hospitalization as a trigger for venous thromboembolism – Results from a population-based case-crossover study 

      Bjøri, Esben; Johnsen, Håkon Sandbukt; Hansen, John-Bjarne; Brækkan, Sigrid Kufaas (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-21)
      <i>Background</i> - Previous studies have reported that around 50% of patients with venous thromboembolism (VTE) has undergone recent hospitalization. However, studies on the impact of hospitalization as a trigger factor for VTE are limited.<p><p> <i>Objectives</i> - To investigate the impact of hospitalization with and without concurrent immobilization as a trigger factor for VTE.<p><p> ...

    • Platelet count and risk of major bleeding in venous thromboembolism 

      Johnsen, Håkon Sandbukt; Brækkan, Sigrid Kufaas; Morelli, Vania Maris; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-05)
      <p>The relationship between platelet count and risk of major bleeding in patients with venous thromboembolism (VTE) during anticoagulation remains unclear. We therefore investigated the association between platelet count, measured at VTE diagnosis and before the thrombotic event, and risk of major bleeding. Participants comprised 744 patients with incident VTE derived from the Tromsø Study. Major ...

    • Prothrombotic genotypes and risk of major bleeding in patients with incident venous thromboembolism 

      Johnsen, Håkon Sandbukt; Bjøri, Esben; Hindberg, Kristian; Brækkan, Sigrid Kufaas; Morelli, Vania Maris; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-22)
      <i>Background</i> - Genotypes associated with venous thromboembolism (VTE) may protect against bleeding due to a hypercoagulable state. Whether the risk of major bleeding is reduced in parallel with an increasing number of prothrombotic genotypes during anticoagulant treatment in VTE remains unknown.<p> <p><i>Objectives</i> - To investigate the association between multiple prothrombotic genotypes ...